Glucosamine HCL, CAS# 66-84-2, is a extraction manufactured through chemical synthesis, available as Crystallion powder,white. D-Glucosamine Hydrochloride is widely used as nutritional supplements. It is widely accepted as safe food additive in many countries. Is there some safety and/or health risk about D-Glucosamine Hydrochloride that consumers need to know? Let's check out some basic facts about this ingredient. GRAS Exemptions: Yes Foodchem Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. D-Glucosamine Hydrochloride is perfectly safe for using as food additives. Suggested Dosage As D-Glucosamine Hydrochloride is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of D-Glucosamine Hydrochloride for long period. Special Groups Precaution Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups. There is no evidence that D-Glucosamine Hydrochloride could have any negative effects on these vulnerable groups. It should be safe to use D-Glucosamine Hydrochloride in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of D-Glucosamine Hydrochloride for long period in food for newborns or pregnant. General Side Effects No significant side effects reported. Reported Health Issues No health issues about D-Glucosamine Hydrochloride reported up to now. Related Research 1. Effect of Fucoxanthin Alone and in Combination with D-glucosamine Hydrochloride on Carrageenan/kaolin-induced Experimental Arthritis in Rats. [Phytother Res. 2014 Jul] Author: Gong D, Chu W, Jiang L, Geng C, Li J, Ishikawa N, Kajima K, Zhong L. 2. Metabolomic analyses of blood plasma after oral administration of D-glucosamine hydrochloride to dogs. [Mar Drugs. 2012 Aug] Author: Osaki T, Azuma K, Kurozumi S, Takamori Y, Tsuka T, Imagawa T, Okamoto Y, Minami S. 3. Improved determination of D-glucosamine hydrochloride in health foods by HPLC using 7-fluoro-4-nitrobenzo-2-oxa-l,3-diazole as a derivative. [J Food Sci. 2011 Nov-Dec] Author: Su G, Wang X, Chi D, Li L, Shao L. 4. Selective inhibition of Newcastle disease virus-induced glycoprotein synthesis by D-glucosamine hydrochloride. [J Virol. 1974 Apr] Author: Samson AC, Fox CF. 5. The effect of exogenously administered D-glucosamine hydrochloride on the seromucoid fraction of tumor-bearing rats. [Cancer Res. 1967 May] Author: Macbeth RA, Akpata M. - See more at: http://www.foodchemadditives.com/side_effects_info/679
